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Courteney Cox | Gloria Dinallo | 16 eps. |
| Dean Paul Martin | Dr. Billy Hayes | 16 eps. | |
| Jennifer Holmes | Jane Miller | 16 eps. | |
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Kevin Peter Hall | Dr. Elvin \'El\' Lincoln | 16 eps. |
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Max Wright | Dick Stetmeyer | 16 eps. |
| Mark Thomas Miller | John \'Johnny B\' Bukowski | 16 eps. | |
| Diane Cary | Miss Nance | 15 eps. | |
| Patricia Wilson | 3 eps. | ||
| Michael McGuire | 2 eps. | ||
| Dawan Scott | 2 eps. |
| 1 | Deep Freeze (Pilot) | 10/04/1985 | |
| 2 | Your Place or Mayan | 10/18/1985 | |
| 3 | Guess What's Coming to Dinner | 10/25/1985 | |
| 4 | Lost Link | 11/01/1985 | |
| 5 | Sort of Looking for Gina | 11/08/1985 | |
| 6 | Sonar... and Yet So Far | 11/15/1985 | |
| 7 | Steer Crazy | 11/29/1985 | |
| 8 | Fumble on the One | 12/06/1985 | |
| 9 | Twin Engines | 12/13/1985 | |
| 10 | Grand Theft Bunny | 12/27/1985 | |
| 11 | Grand Elusion | 01/10/1986 | |
| 12 | Once Upon a Night | 01/17/1986 | |
| 13 | Center of Attention | 01/31/1986 | |
| 14 | Against All Oz | 02/07/1986 | |
| 15 | The Avenging Angel | 02/21/1986 | |
| 16 | Three Days of the Blender |
| Name | Misfits of Science |
| Status | Returning Series |
| Date of 1st Airing | Oct. 4, 1985 |
| Date of Last Airing | |
| Show Type | |
| Original Air Day | Monday |
| Original Air Time | |
| Show Length | 30 |
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